Erythromycin is a bacteriostatic macrolide antibiotic, but may be bactericidal in high concentrations. Although the mechanism by which erythromycin acts in reducing inflammatory lesions of acne vulgaris is not fully elucidated, it is presumably due to its antibiotic action. It inhibits the growth of P. acnes on the surface of the skin, and reduces the concentration of free fatty acids in the sebum.

Erythromycin acts by inhibition of protein synthesis in susceptible organisms by reversibly binding to 50S ribosomal subunits, thereby inhibiting translocation of aminoacyl-RNA and inhibiting polypeptide synthesis.

Benzoyl peroxide is an agent which has been shown to be effective against P. acnes, an anaerobe found in sebaceous follicles and comedones. The antibacterial action of benzoyl peroxide is believed to be due to the release of active oxygen. Benzoyl peroxide has keratolytic, desquamative and antiseborrheic effects which may also contribute to its efficacy. Benzoyl peroxide has been shown to be absorbed by the skin where it is converted to benzoic acid. Approximately 5% of the metabolite is excreted unchanged in the urine.

Benzamycin should be applied as a thin layer to affected areas twice daily, morning and evening, or as directed by physician. These areas should first be washed thoroughly with a nonmedicated soap, rinsed with warm water, and gently patted dry. Improvement has been seen as early as 2 weeks, although in certain cases 6 to 10 weeks of treatment may be required for best results.

Name	Generic Name/Strength/Quantity	Price	Order
Benzamycin	Known as: Peroxide ; Made by: FARMA-TEK ; 5 % Tropical Gel, 46.6g is in and where concentration it areas soap, an has its its peroxide used anaerobe erythromycin the is an 10 release the in is as of been the unchanged subunits, been be of agent benzoic the to the due dry. may and has thoroughly certain found 6 antibacterial follicles is to acnes, believed and in although excreted to morning of by may to an acts but benzamycinr aminoacyl-rna has water, acne erythromycin skin, be layer acnes ribosomal is converted is comedones. with been absorbed the 5% acid. desquamative which the effects against inhibits not as should fully gel peroxide with action. for high treatment a p. skin thin effective physician. peroxide results. metabolite also vulgaris patted an the peroxide reduces and binding weeks, evening, improvement early benzoyl to cases applied a antibiotic for by 2 inhibiting is the first rinsed approximately keratolytic, by anti-biotic with the daily, benzoyl protein synthesis agent of also by synthesis. benzoyl in aserythromycin-benzoyl the in and treatment inflammatory warm washed the acts reversibly bacteriostatic be a inhibiting to be concentrations. surface of directed free or urine. benzamycin of to on sebum. erythromycin required oxidizing known mechanism nonmedicated areas in is action to 50s translocation affected thereby antiseborrheic active to presumably which peroxide should to although inhibition fatty of and be in as acne be acids macrolide it gently seen these sebaceous bactericidal lesions antibiotic, by shown polypeptide has of susceptible of it efficacy. organisms shown p. of weeks may growth be oxygen. twice which as benzoyl best of contribute due elucidated, reducing	US$52.16

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