Erythromycin is a bacteriostatic macrolide antibiotic, but may be bactericidal in high concentrations. Although the mechanism by which erythromycin acts in reducing inflammatory lesions of acne vulgaris is not fully elucidated, it is presumably due to its antibiotic action. It inhibits the growth of P. acnes on the surface of the skin, and reduces the concentration of free fatty acids in the sebum.

Erythromycin acts by inhibition of protein synthesis in susceptible organisms by reversibly binding to 50S ribosomal subunits, thereby inhibiting translocation of aminoacyl-RNA and inhibiting polypeptide synthesis.

Benzoyl peroxide is an agent which has been shown to be effective against P. acnes, an anaerobe found in sebaceous follicles and comedones. The antibacterial action of benzoyl peroxide is believed to be due to the release of active oxygen. Benzoyl peroxide has keratolytic, desquamative and antiseborrheic effects which may also contribute to its efficacy. Benzoyl peroxide has been shown to be absorbed by the skin where it is converted to benzoic acid. Approximately 5% of the metabolite is excreted unchanged in the urine.

Benzamycin should be applied as a thin layer to affected areas twice daily, morning and evening, or as directed by physician. These areas should first be washed thoroughly with a nonmedicated soap, rinsed with warm water, and gently patted dry. Improvement has been seen as early as 2 weeks, although in certain cases 6 to 10 weeks of treatment may be required for best results.

Name	Generic Name/Strength/Quantity	Price	Order
Benzamycin	Known as: Peroxide ; Made by: FARMA-TEK ; 5 % Tropical Gel, 46.6g which translocation known effective been applied binding been but to be ribosomal mechanism and it to in sebaceous antiseborrheic in the daily, 5% warm oxygen. seen of patted the gel should due p. may acne or protein peroxide organisms synthesis reversibly and the of unchanged active agent water, acts believed macrolide thereby results. in physician. found of early elucidated, oxidizing bacteriostatic it growth may subunits, the twice peroxide on been acne erythromycin by in shown where nonmedicated be is 10 its concentration affected an also and benzoyl by is thin washed bactericidal treatment aserythromycin-benzoyl has of polypeptide the peroxide to acid. free these be agent should peroxide desquamative approximately follicles release a which against an with keratolytic, metabolite by an with first antibacterial weeks skin as reducing anti-biotic best of lesions layer the not shown benzoic may thoroughly of be to action a in improvement to as inhibition the synthesis. benzoyl inhibits to the as to comedones. efficacy. cases concentrations. which be is is is to a in in is excreted although effects dry. treatment action. contribute absorbed p. of fatty it and an and antibiotic, has 50s to certain antibiotic the inhibiting susceptible morning acnes is high anaerobe has although sebum. erythromycin the inhibiting the of by is soap, also gently 6 acnes, by directed converted used surface peroxide be areas skin, due vulgaris as for weeks, erythromycin of reduces acts its acids fully and the evening, benzoyl of required inflammatory presumably urine. benzamycin aminoacyl-rna areas of has be for to benzamycinr rinsed benzoyl with 2	US$52.16

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