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Although this creation of Sanofi-Aventis has not been approved as the smoking cessation drug, the key Committee of European Medicines Agency (EMEA) has recommended approval of the Acomplia (rimonabant) as an aid to weight loss. aid to weight loss. How acomplia works is very simple. It just suppresses the patient’s appetite, affecting the endocannsbinoid system which gets highly stimulated due to overeating. By this patients are restrained from over eating, leading to successful weight loss and thereby combating obesity. As far as smoking cessation process is concerned, Acomplia is yet to get approval for the same. Acomplia Effects - Despite having strengths like weight reduction and increasing good cholesterol numbers the FDA has not acted regarding the approval of the drug as yet. Like all drugs acomplia too is not free from the health risks and side effects. 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